Here you'll find useful information about the Sinclair Method to treat Alcohol Use Disorder.

The Sinclair Method is referred to medically as Pharmacological Extinction.

The Sinclair Method is based on medical science from Europe.

The treatment we offer builds on the Sinclair Method by combining coaching or therapy.

By combining best-in-class coaching or therapy techniques, we produces jaw-dropping results in the shortest time possible.


Now available in California, Connecticut, DC, Florida, Georgia, Maine, Maryland, Massachusetts, New Jersey, and Rhode Island

Click on the links below to see the studies that back our method.

This 2012 Mitchell study, out of the University of San Francisco, proved that alcohol releases endorphins (also called "endogenous opioids") which are the body's naturally produced version of an opioid that simply reinforce the act of drinking.

This 2009 study, from the Waggoner Center for Alcohol and Addiction Research in Texas, explains how the alcohol molecule also "mimics" GABA, a naturally occurring neurochemical that slows neuronal firing to produce a calming effect,the reason most people drink. Opioid-blocking medication doesn't block GABA, making extinction of Alcohol Use Disorder relatively effortless. How? The overall "drinking experience" is not affected. Just the endorphins are blocked, a hardly noticeable effect.

This 2008 study, from the University of Indianapolis, explains the "alcohol deprivation effect," which is nearly identical to "yo-yo" dieting for people attacking a weight issue through will-power alone. With Alcohol Use Disorder, we call this "relapse." Our treatment method will eliminate relapse once you cement the habit of as-needed use of the medication we prescribe any time you choose to drink in the future. It's easy to do. The chart below demonstrates the basic "yo-yo" trajectory of drinking caused by the alcohol deprivation effect.

This 2001 study, put out by the Finnish National Public Health Institute and authored by the scientist that invented the "Sinclair Method," explains the basics of Pharmacological Extinction.

This 2013 European article summarizes two large-scale patient studies testing a second-generation opioid-blocker to achieve similar results in extinguishing Alcohol Used Disorder as the Finnish studies produced. In 2014, Pharmacological Extinction combined with therapy was officially approved by the European Union's version of the FDA as an effective treatment model and is now widely available for treating Alcohol Use Disorder in other European countries besides just Finland.

This 2006 study from the University of Pennsylvania explains how professional counseling improves the outcome of medication assisted treatment of Alcohol Use Disorder.